Statins will help beat back the specter of coronary heart illness by lowering the manufacturing of ldl cholesterol contained in the liver. The cholesterol-lowering medication have doubtlessly saved thousands and thousands of lives however their results usually are not fully benign. Statins don’t combine effectively with grapefruit juice. Mixing the 2 could be perilous.

Harvard Health explains: “Certain classes of drugs — most notably statins — are metabolised (broken down) in your intestines by an enzyme called CYP3A, which normally reduces the amount of drug that enters your bloodstream.

“Grapefruit juice accommodates compounds referred to as furanocoumarins that cease CYP3A from doing its job. As a outcome, extra of the drug is absorbed, making it extra highly effective than it is meant to be — even poisonous in some circumstances.”

It’s worth noting that not all statins are affected equally by grapefruit juice, so grapefruit fans might want to switch to a statin that’s less affected.

Grapefruit juice has the biggest effect on the following statins:

  • Atorvastatin
  • Lovastatin
  • Simvastatin.

READ MORE: Warning: Woman who ate the same fruit daily almost lost her leg from dangerous blood clot

Currently, healthcare professionals advise it is safe to drink grapefruit juice and eat grapefruit if you’re taking other types of statins, notes the NHS.

If you can’t switch, experts say it’s probably okay to enjoy a small glass.

“That’s as a result of the research exhibiting harmful results used huge quantities of furanocoumarins, the quantity present in a quart or extra of the juice,” explains Harvard Health.

It adds: “What’s extra, consuming half a grapefruit is even much less dangerous than consuming grapefruit juice, because it takes a number of fruits to make a single glass of juice.”

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Other interactions

“The physician may even ask you ways a lot alcohol you drink earlier than prescribing statins,” explains the NHS.

According to the health body, people who regularly drink large amounts of alcohol are at increased risk of getting more serious side effects.

“If you are prescribed a statin, you might be able to proceed consuming alcohol.”

However, you should not drink more than 14 units of alcohol a week – this the recommended UK guidelines.

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14 units is equivalent to six pints of average-strength beer or 10 small glasses of lower-strength wine.

Natural ways to lower high cholesterol

You can lower your cholesterol by eating healthily and getting more exercise.

According to the British Heart Foundation (BHF), things that cause high cholesterol you can control include:

  • Eating too much saturated fat
  • Not being active enough
  • Having too much body fat, especially around your middle.

“Smoking can result in excessive levels of cholesterol, and the build-up of tar it causes in your arteries makes it simpler for ldl cholesterol to stay to your artery partitions,” warns the BHF.

If you’re chubby or have diabetes, you’re at better danger of getting excessive ldl cholesterol, notes the well being physique.

Type 2 diabetes is a standard situation that causes the extent of sugar (glucose) within the blood to develop into too excessive.

Reporting unwanted side effects of statins

The Yellow Card Scheme permits you to report suspected unwanted side effects from any kind of medication you are taking.

It’s run by a medicines security watchdog referred to as the Medicines and Healthcare merchandise Regulatory Agency (MHRA).